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VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic proﬁles enhances PD-1 response

3 points

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Posted 384 days ago

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice

2 points

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Posted 384 days ago

High glucose levels accelerate atherosclerosis via NLRP3-IL/ MAPK/NF-κB-related inflammation pathways

5 points

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Posted 384 days ago

Detection of Constitutional Structural Variants by Optical Genome Mapping

2 points

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Posted 384 days ago

CLEC-1 Restrains Acute Inflammatory Response and Recruitment of Neutrophils following Tissue Injury

2 points

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Posted 384 days ago

A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome

3 points

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Posted 382 days ago

Fosgonimeton attenuates amyloid-beta toxicity in preclinical models of Alzheimer's disease

4 points

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Posted 379 days ago

High positive predictive value 22q11.2 microdeletion screening by prenatal cell-free DNA testing that incorporates fetal fraction amplification

2 points

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Posted 369 days ago

Sargramostim for Prophylactic Management of Gastrointestinal Immune-Related Adverse Events of Immune Checkpoint Inhibitor Therapy for Cancer

2 points

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Posted 369 days ago

The mechanism of action, pharmacological characteristics, and clinical utility of the amyloid depleter birtamimab for the potential treatment of AL amyloidosis

3 points

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Posted 369 days ago

Synthesis and Structure–Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT2 Receptor Agonist

3 points

|

Posted 369 days ago

Behavioral changes in patients with Prader-Willi syndrome receiving diazoxide choline extended-release tablets compared to the PATH for PWS natural history study

3 points

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Posted 358 days ago

RNA aggregates harness the danger response for potent cancer immunotherapy

4 points

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Posted 358 days ago

MYTX-011: a pH-dependent anti-cMET antibody-drug conjugate designed for enhanced payload delivery to cMET expressing tumor cells

4 points

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Posted 353 days ago

Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for Pancreatic Ductal Adenocarcinoma

3 points

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Posted 353 days ago

Serial Postoperative Circulating Tumor DNA Assessment Has Strong Prognostic Value During Long-Term Follow-Up in Patients With Breast Cancer

2 points

|

Posted 353 days ago

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