Syncell, a company specializing in subcellular spatial proteomics, has announced a new strategic co-marketing agreement with Thermo Fisher Scientific. The collaboration aims to bring a comprehensive, high-resolution spatial proteomics workflow to the market by combining Syncell's proprietary Microscoop® technology with Thermo Fisher's Orbitrap™ Astral™ mass spectrometers. This partnership creates a new, integrated system for researchers to analyze and map proteins within cells and tissues with unprecedented detail and precision.
The combined workflow represents a significant advancement over traditional, antibody-based spatial methods. By integrating Syncell's Microscoop Mint—a high-precision system that purifies proteins from specific regions of a cell—with the ultra-sensitive and high-speed Orbitrap™ Astral™ mass spectrometer series, the collaboration enables researchers to perform unbiased protein mapping without relying on predefined targets. This allows for a deeper, more comprehensive understanding of protein organization and function in a wide range of biological systems.
According to Dr. Jung-Chi Liao, CEO of Syncell, this partnership reinforces the company's mission to make high-resolution spatial proteomics accessible to more researchers. Dr. Luisa Iruela-Arispe of Northwestern Medicine also highlighted the transformative potential of the combined technology, stating that it "pushes the boundaries of cell signaling" and reveals "spatial and chemical detail that has never before been accessible."
The integrated system provides a hypothesis-free approach to subcellular proteome analysis, which has broad applications across various scientific fields, including oncology, neuroscience, drug discovery, and immunology. Researchers can use the technology on both fresh tissue samples and formalin-fixed, paraffin-embedded (FFPE) tissues, as well as cell cultures.
By delivering unmatched acquisition speed and proteome depth, the collaboration between Syncell and Thermo Fisher is poised to set a new standard for high-resolution proteomic discovery, opening up new avenues for scientific exploration and discovery at the cellular and subcellular level.