Oregon Therapeutics is a French preclinical biotech developing PDI inhibitors issued from groundbreaking drug discovery programs. Oregon has developed XCE853 up to regulatory preclinical stage entry and demonstrated XCE853’s disruptive potential as “first in class” and “best in class” candidate in oncology. Oregon Therapeutics’ first objective is to bring XCE853 into Clinical Phase for the treatment of cancers in collaboration with Lantern Pharma. Based on the scientific rationale to exploit metabolic vulnerability of some cancers, the two priority indications are ovarian cancer and advanced pancreatic cancer. Potential additional indications include liver, prostate, head and neck and several orphan cancers.