Matinas BioPharma is a biopharmaceutical company focused on delivering groundbreaking therapies using its lipid nanocrystal (LNC) platform delivery technology to maximize global clinical impact and patient access. The Company is developing its own internal portfolio of products as well as partnering with leading pharmaceutical companies to develop novel formulations that capitalize on the unique characteristics of the LNC platform. Preclinical and clinical data have demonstrated that this novel technology can provide solutions to many of the challenges in achieving safe and effective intracellular delivery for both small molecules and larger, more complex molecules such as siRNA, antisense oligonucleotides, and vaccines. The combination of a unique mechanism of action and flexibility with formulation and route of administration (including oral) positions Matinas’ LNC technology potentially to become a preferred next-generation intracellular drug delivery platform. In addition, Matinas has recently developed a non-LNC phosphatidylserine-based nanoparticle delivery technology that takes advantage of the same unique biological properties of phosphatidylserine that play a key role in more traditional LNCs, but with its own unique structural characteristics that allow the in vitro and in vivo delivery of larger oligonucleotides like mRNA, with several distinct potential advantages over lipid nanoparticle alternatives.

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