Juvena Therapeutics is a computationally-driven biopharmaceutical company on a mission to develop disease-modifying biologics to treat chronic muscle and metabolic diseases. The company’s approach stems from unlocking the therapeutic potential of stem-cell secreted proteins and translating them into a growing pipeline of engineered biologics. In addition to JUV-161, Juvena is progressing multiple preclinical programs, including a novel obesity asset with a unique mechanism. Juvena is achieving this through a fully integrated, end-to-end Artificial Intelligence (AI)-enabled drug discovery and development platform that combines a compounding database mapping secreted proteins to specific disease phenotypes, in silico and in vitro human cell screening, pharmacology, and protein engineering capabilities.